Professor Ehud Gazit

Professor Ehud Gazit is an Israeli biochemist, biophysicist and nanotechnologist. He is Professor and Endowed Chair at Tel Aviv University and a Member of the Executive Board of the University since 2017. Gazit received his Bachelor of Science with summa cum laude at Tel Aviv University, and his Ph.D. with highest distinction at the Weizmann Institute of Science. For his Ph.D. work, he received the John F. Kennedy Award in 1996. Professor Gazit has been a faculty member at Tel Aviv University since 2000, after completing his postdoctoral studies as a European Molecular Biology Organization (EMBO) and Human Frontiers Science Program (HFSP) fellow at Massachusetts Institute of Technology (MIT).

Professor Gazit has received numerous awards and honors including the Landau Research Award, Dan David Scholarship Award and Prize for excellence in research from the Research Council of Tel Aviv University. In 2009, he received the Hestrin Award for a leading scientist under the age of 44. In 2012 he was elected as a fellow of the Royal Society of Chemistry (FRSC). In 2015 he was awarded with the Kadar Family Prize and elected as a member in the European Molecular Organization (EMBO).

List of Top 20 Publications

  1. Gazit, E.* (2002) The “Correctly-Folded” State of Proteins: Is it a Metastable State? Angew. Chem. Int. Ed. Engl. 41, 257-259 (English) / Gazit E.* (2002) "Korrekt gefaltete" Protein - ein metastabiler Zustand? Angew. Chem. 114, 267-269 (German).
  2. Reches, M., & Gazit, E.* (2003) Casting Metal Nanowires within Discrete Self-Assembled Peptide Nanotubes. Science 300, 625-627.
  3. Carny, O. & Gazit, E.* (2005) A Model for the Role of Short Self-Assembled Peptides in the very Early Stages of the Origin of Life. FASEB J. 19, 1051-1055.
  4. Reches, M., & Gazit, E.* (2006) Controlled Patterning of Aligned Self-Assembled Peptide Nanotubes. Nature Nanotech. 1, 195-200. (Featured on the cover of the issue and in a "News and Views" article at: Nature Nanotech. 1, 169-170).
  5. Mahler, A., Reches, M., Rechter, M., Cohen, S. & Gazit, E.* (2006). Rigid, Self-Assembled Hydrogel Composed of a Modified Aromatic Dipeptide. Adv. Mater. 18, 1365-1370.
  6. Adler-Abramovich, L., Aronov, D., Beker, P., Yevnin, M., Stempler, S., Buzhansky, L., Rosenman, G.*, & Gazit, E.* (2009) Self-assembled Arrays of Peptide Nanotubes by Vapour Deposition. Nature Nanotech. 4, 849-854.
  7. Adler-Abramovich, L., Vaks, L., Carny, O., Trudler, D., Frenkel, D., & Gazit, E.* (2012) Phenylalanine Assembly into Toxic Fibrils Suggests Amyloid Etiology in Phenylketonuria. Nature Chem. Biol. 8, 701-706. (Featured on the cover of the issue).
  8. Berger, O., Adler-Abramovich, L., Levy-Sakin, M., Grunwald, A., Liebes-Peer, Y., Bachar, M., Buzhansky, L., Mossou, E., Forsyth, V.T., , Schwartz, T., Ebenstein, Y., Frolow, F., Shimon, L. J. W., Patolsky, F., & Gazit, E.* (2015) Light-Emitting Self-Assembled Peptide Nucleic Acids Exhibit both Stacking Interactions and Watson-Crick Base Pairing. Nature Nanotech. 10, 353-360 [Featured on the cover of the issue as well as on the cover of the 10th anniversary issue of Nature Nanotechn (October 2016 – "A decade of small wonders"), and in a "News and Views" article at: Nature Nanotech. 10, 295-296].
  9. Shaham-Niv, S., Adler-Abramovich, L., Schnaider, L., & Gazit, E.* (2015) Extension of the Generic Amyloid Hypothesis to Non-Proteinaceous Metabolite Assemblies. Science Adv. 1, e1500137.
  10. Mondal, S., Adler-Abramovich, L., Lipman, S., & Gazit E.* (2016) Formation of Functional Super-Helical Assemblies by Constrained Single Heptad Repeat. Nature Commun. 6, 8615.
  11. Levin, A., Michaels, T. C. T., Adler-Abramovich, L., Mason, T. O., Mueller, T., Mahadevan, L., Gazit, E.*, & Knowles, T. P. J.* (2016) Elastic Instability-Mediated Actuation by a Supramolecular Polymer. Nature Physics 12, 926–930.
  12. Guterman, T., Kornreich, M., Stern, A., Adler-Abramovich, L., Porath, D., Beck, R., Shimon, L., & Gazit, E.* (2016) Formation of Bacterial Pilus-Like Nanofibers by Designed Minimalistic Self-Assembling Peptides. Nature Commun. 7, 13482.
  13. Tao, K., Makam, P., Aizen, R., & Gazit, E.* (2017) Self-Assembling Peptide Semiconductors. Science 358, eaam9756.
  14. Schnaider, L., Brahmachari, S., Schmidt, N.W., Mensa, B., Shaham-Niv, S., Bychenko, D., Adler-Abramovich, L., Shimon, L.J.W., Kolusheva, S., DeGrado, W. F.*, & Gazit, E.* (2017) Self-Assembling Dipeptide Antibacterial Nanostructures with Membrane Disrupting Activity. Nature Commun. 8, 1365.
  15. Yuan, C., Ji, W., Xing, R., Li, J.*, Gazit, E.*, & Yan, X.* (2019) Hierarchically Oriented Organization in Supramolecular Peptide Crystals. Nature Rev. Chem. 3, 567–588. 
  16. Laor, D., Sade, D., Shira Shaham-Niv, S., Zaguri, D., Gartner, M., Basavalingappa, V., Raveh, A., Pichinuk, E., Engel, H., Iwasaki, K., Yamamoto, T., Noothalapati, H., & Gazit, E.* (2019) Fibril Formation and Therapeutic Targeting of Amyloid-Like Structures in a Yeast Model of Adenine Accumulation. Nature Commun. 10, 62.
  17. Bera, S., Mondal, S., Xue, B., Shimon, L. J. W., Cao, Y., & Gazit, E.* (2019) Rigid Helical-like Assemblies from a Self-Aggregating Tripeptide. Nature Mater. 18, 503–509.
  18. Makam, P., Yamijala, S. S. R. K. C., Tao, K., Shimon, L. J. W., Eisenberg, D. S., Sawaya, M. R., Wong, B. M., & Gazit, E.* (2019) Nonproteinaceous Hydrolase Comprised of Phenylalanine Metallosupramolecular Amyloid-Like Structure. Nature Catal. 2, 977–985. (Featured in a "News and Views" article at: Nature Catal. 2, 949–950).
  19. Levin, A., Hakala, T., Schnaider, L., Bernardes, G., Gazit, E. & Knowles, T.P.J. (2020) Biomimetic Peptide Self-Assembly for Functional Materials. Nature Rev. Chem. 4, 615-634.
  20. Tao, K., Tang, Y., Rencus-Lazar, S., Yao, Y., Xue, B., Gilead, S., Wei, G. & Gazit, E.* (2020) Bioinspired Supramolecular Packing Enables High Thermo-Sustainability. Angew. Chem. Intl. Ed. 59, 19037-19041 (Selected as "Hot Paper" by the journal).